Newberry College's 90-acre, wooded campus is located less than a mile from local shopping areas in the small town of Newberry, SC. The College's 32 buildings and athletic facilities are well-equipped to serve student needs. The College centers on a quadrangle that is heavily planted with azaleas, and other trees and shrubs.

Conveying special charm to the quadrangle are the four campus buildings listed in the National Register of Historic Places: Smeltzer Hall, Keller Hall, Holland Hall, and Derrick Hall. These four buildings ring three sides of the quadrangle. On the fourth side are the McClurg Center for Teaching and Learning, Langford Communications Center, and Wessels Library.

The Herman Langford Communications Center, completed in 1990, has state-of-the-art communications facilities including a TV studio, radio station, as well as audio and video production suites. The McClurg Center, along with the nearby Science and Mathematics Building, house classrooms, seminar rooms, science and computer laboratories, art studios, and offices.
Wessels Library
Wessels Library houses a comprehensive collection of books, periodicals, and non-print materials. Through its Inter-Library arrangements, students have access to research materials throughout the nation. In the Special Collections room of the Library are many historical documents relating to Lutheranism and to the local area as well as a special facsimile of the Book of Kells.

One of the most easily visible buildings on campus is Wiles Chapel with its soaring steeple and neo-gothic design, and neo-impressionistic stained glass windows. It houses a 1,000 seat chapel where convocations and interfaith services are held.

Two other important buildings for learning include the Alumni Music Center and the Physical Education Complex. The Alumni Music Center houses a 150-seat recital hall, practice rooms, a band room, offices, and classrooms. The Physical Education Complex houses the 1,600-seat Eleazer basketball arena, racquetball courts, stress lab, offices, and classrooms. Other athletic facilities include the lighted tennis courts, Setzler Field, a 4,000-seat football stadium, the John F. Clarkson outdoor swimming pool, the H. Lee Atwater Field, a combination soccer/softball field, as well as intramural and other playing fields.

The O. L. Casey Center adjoins the swimming pool and the Physical Education Complex. It houses the Athletic Department. 

Since campus living is an integral part of a college education, Newberry encourages all students to live on campus unless they are married or residing with family members. Six residence halls offer facilities for men and women. Each hall has lounges and study areas in addition to student rooms.

Meals are served every day in Kaufmann Hall where the post office, snack bar and college bookstore are located.